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, 11:04, 25 May 2010
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| '''New Fugue''' is a program for estimation of haplotype frequencies and linkage disequilibrium coefficients in family data. The current implementation uses the methods described by Abecasis and Wigginton (2005) and originally implemented in the [http://www.sph.umich.edu/csg/abecasis/Merlin Merlin package]. | | '''New Fugue''' is a program for estimation of haplotype frequencies and linkage disequilibrium coefficients in family data. The current implementation uses the methods described by Abecasis and Wigginton (2005) and originally implemented in the [http://www.sph.umich.edu/csg/abecasis/Merlin Merlin package]. |
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− | == Command Line Options ==
| + | = Command Line Options = |
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− | === Input Files ===
| + | == Input Files == |
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| ; -d ''datafile'' | | ; -d ''datafile'' |
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| : Output file prefix. | | : Output file prefix. |
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− | === Frequency Estimates ===
| + | == Frequency Estimates == |
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| ; --alleles | | ; --alleles |
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| : Estimate maximum likelihood haplotype frequencies | | : Estimate maximum likelihood haplotype frequencies |
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− | === Linkage Disequilibrium Estimates ===
| + | == Linkage Disequilibrium Estimates == |
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| ; --diseq | | ; --diseq |
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| : Only report linkage disequilibrium for marker pairs that include ''marker'' | | : Only report linkage disequilibrium for marker pairs that include ''marker'' |
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− | === Linkage Disequilibrium File Options ===
| + | == Linkage Disequilibrium File Options == |
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| ; --ids | | ; --ids |
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| ; --minrsq | | ; --minrsq |
| : only record markers that have rsq greater than a specific threshold | | : only record markers that have rsq greater than a specific threshold |
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| == Download == | | == Download == |