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MaCH FAQ

33 bytes added, 16:36, 19 November 2010
How long does imputation take?
#r, # of rounds (-r or --rounds, --mle corresponds to 1-2 rounds)
Computational time increases linearly with m, n, r and quadratically with h. On our Xeon 3.0GHz machine, imputation with m=25K, n=250, h=120, and r=100 takes ~20 hours(25000*250*120^2*100/4.5/10^11).
If you have a larger number of individuals to impute (e.g., > 1,000), we recommend a 2-step imputation manner http://genome.sph.umich.edu/wiki/MaCH_FAQ#Why_and_how_to_perform_a_2-step_imputation.3F.
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