Changes

If you are doing imputation only once (think twice if this is really true) or under an immediate time pressure, you can use MaCH-Admix, which does not require pre-phased data and takes ~1/7 of the computing time of the original MaCH. For large dataset, we recommend breaking the genome into small overlapping segments ( [http://genome.sph.umich.edu/wiki/MaCH_FAQ#Divide_and_Conquer Divide-and-Conquer]).Details see www.sph.umich.edu/csg/yli/MaCH-Admix/