Changes

== Key Features ==

== Key Features ==

'''Rare Metal''' has the following features:

'''Rare Metal''' has the following features:

* '''Rare Metal''' performs meta analysis using gene-based Burden tests with the following methods: CMC_counts, Madsen-Browning, SKAT, and Variable Threshold.  

* '''Rare Metal''' performs gene-based or region-based meta analysis using Burden tests with the following methods: CMC_counts, Madsen-Browning, SKAT, and Variable Threshold.  

* '''Rare Metal''' performs single variant metal-analysis by default.  

* '''Rare Metal''' performs single variant metal-analysis by default.  

* '''Rare Metal''' allows customized groups of variants to be tested.

* '''Rare Metal''' allows customized groups of variants to be tested.