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| | | |
| == Lastest ChangeLog == | | == Lastest ChangeLog == |
− | == Full ChangeLog ==
| + | * March 25th, 2013 : EPACTS v3.2.3 release |
| + | ** Relaxed the checking of low-rank matrix in SKAT tests (to avoid unncessary skipping of genes) |
| * March 13th, 2013 : EPACTS v3.2.2 release | | * March 13th, 2013 : EPACTS v3.2.2 release |
− | * Fixed an error which occasionally report mismatches in the number of samples | + | ** Fixed an error which occasionally report mismatches in the number of samples |
| * March 9th, 2013 : EPACTS v3.2.1 release | | * March 9th, 2013 : EPACTS v3.2.1 release |
| **Fixed errors in loading the dynamic library | | **Fixed errors in loading the dynamic library |
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| If you want to use EPACTS in an Ubuntu platform, following the step below | | If you want to use EPACTS in an Ubuntu platform, following the step below |
| | | |
− | *Download EPACTS source distribution at http://www.sph.umich.edu/csg/kang/epacts/download/EPACTS-3.2.2.tar.gz (100MB) | + | *Download EPACTS source distribution at http://www.sph.umich.edu/csg/kang/epacts/download/EPACTS-3.2.3.tar.gz (100MB) |
| *Uncompress EPACTS package, and install the package using the following set of commands | | *Uncompress EPACTS package, and install the package using the following set of commands |
| | | |
− | tar xzvf EPACTS-3.2.2.tar.gz | + | tar xzvf EPACTS-3.2.3.tar.gz |
− | cd EPACTS-3.2.2 | + | cd EPACTS-3.2.3 |
| ./configure --prefix=/path/to/install | | ./configure --prefix=/path/to/install |
| make | | make |
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| 20 1616892 1616892 20:1616892_A/G_Synonymous:SIRPG 266 144 1 0.27068 0.0051239 2.7991 145 121 0.63449 0.42975 | | 20 1616892 1616892 20:1616892_A/G_Synonymous:SIRPG 266 144 1 0.27068 0.0051239 2.7991 145 121 0.63449 0.42975 |
| 20 25038372 25038372 20:25038372_G/A_Intron:ACSS1 266 103.3 1 0.19418 0.005748 2.7618 145 121 0.47201 0.28813 | | 20 25038372 25038372 20:25038372_G/A_Intron:ACSS1 266 103.3 1 0.19418 0.005748 2.7618 145 121 0.47201 0.28813 |
| + | |
| + | The key columns represents: |
| + | * '''NS''' : Number of phenotyped samples with non-missing genotypes |
| + | * '''AC''' : Total Non-reference Allele Count |
| + | * '''CALLRATE''' : Fraction of non-missing genotypes. |
| + | * '''MAF''' : Minor allele frequencies |
| + | * '''PVALUE''' : P-value of single variant test |
| + | * '''AF.CASE''' : Non-reference allele frequencies for cases |
| + | * '''AF.CTRL''' : Non-reference allele frequencies for controls |
| | | |
| ==== Q-Q plot of test statistics (stratified by MAF) ==== | | ==== Q-Q plot of test statistics (stratified by MAF) ==== |
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| | | |
| == Full ChangeLog == | | == Full ChangeLog == |
| + | * March 25th, 2013 : EPACTS v3.2.3 release |
| + | ** Relaxed the checking of low-rank matrix in SKAT tests (to avoid unncessary skipping of genes) |
| + | * March 13th, 2013 : EPACTS v3.2.2 release |
| + | ** Fixed an error which occasionally report mismatches in the number of samples |
| * March 9th, 2013 : EPACTS v3.2.1 release | | * March 9th, 2013 : EPACTS v3.2.1 release |
| **Fixed errors in loading the dynamic library | | **Fixed errors in loading the dynamic library |