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RAREMETAL Documentation

201 bytes added, 21:50, 7 August 2013
Brief Description
== Brief Description ==
'''rareMETAL ''' is a computationally efficient tool for meta-analysis of rare variants from genotype arrays and using sequencingor genotyping array data. '''rareMETAL can combine ''' takes summary statistics of individual studies and LD matrices generated by [[Rare-Metal-Worker|'''rareMetalWorker''']]. It provides a convenient approach for , handles related and unrelated individuals, and supports both single variant and gene-level burden meta-analysis of rare variants from various studies. An R-package using the same methodology is [[RareMetals|available]]]. '''rareMETAL''' is developed by Shuang Feng, when joint-analysis of raw data from these studies are restrictedDajiang Liu and Gonçalo Abecasis. Manuscript for this tool is in preparation. Please contact sfengsph at umich dot edu for questions.
== Approach ==
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