From Genome Analysis Wiki
'''rareMETAL''' is a computationally efficient tool for meta-analysis of rare variants using sequencing or genotyping array data. '''rareMETAL''' takes summary statistics and LD matrices generated by [[Rare-Metal-Worker|'''rareMetalWorker''']], handles related and unrelated individuals, and supports both single variant and burden meta-analysis. '''rareMETAL''' generated high quality plots by default and has options that allow users to build reports at different levels.
'''rareMETAL''' is developed by Shuang Feng, Dajiang Liu and Gonçalo Abecasis.
An R-package using the same methodology is [[RareMetals|available]]]. Manuscript for this tool is in preparation. Please contact sfengsph at umich dot edu for questions.
== Approach ==