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The file StatisticSummaryFile.txt in the output directory contains enrichment results with the following information:
The file StatisticSummaryFile.txt in the output directory contains enrichment results with the following information:
Bed_File: The BED file containing the positions for a particular functional domain
Bed_File: The individual datasets used in the enrichment analysis
InBed_Index_SNP: Number of index SNPs or LD proxies (r2>0.7) that overlaps BED file
InBed_Index_SNP: Number of index SNPs or LD proxies (r2>0.7) that overlaps regulatory regions in each dataset
Pvalue: P-value calculated assuming a sum of binomial distributions to represent the number of index SNPs (or LD proxies) that overlap a BED file compared to the expectation observed in the matched control sets
Pvalue: P-value calculated assuming a sum of binomial distributions to represent the number of index SNPs (or LD proxies) that overlap a dataset compared to the expectation observed in the matched control sets
== Acknowledgements ==
== Acknowledgements ==
FallInBed is the result of collaborative efforts by Cristen Willer, Jin Chen, Wei Zhou, Ellen Schmidt, He Zhang, and Goncalo Abecasis. Please email Cristen Willer [cristen@umich.edu] for any questions.
FallInBed is the result of collaborative efforts by Cristen Willer, Jin Chen, Wei Zhou, Ellen Schmidt, He Zhang, and Goncalo Abecasis. Please email Cristen Willer [cristen@umich.edu] for any questions.
