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2 bytes added ,  14:23, 10 September 2013
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* Another option is to use VCF as input. Please refer to the following link for VCF file specification: [http://www.1000genomes.org/wiki/Analysis/Variant%20Call%20Format/vcf-variant-call-format-version-41 1000 genome wiki VCF specs]  
 
* Another option is to use VCF as input. Please refer to the following link for VCF file specification: [http://www.1000genomes.org/wiki/Analysis/Variant%20Call%20Format/vcf-variant-call-format-version-41 1000 genome wiki VCF specs]  
 
* VCF file should be compressed by bgzip and indexed by tabix, using the following command:
 
* VCF file should be compressed by bgzip and indexed by tabix, using the following command:
   bgzip input.vcf    ## this command will produce input.vcf.gz
+
   bgzip input.vcf    ## this command will generate input.vcf.gz
   tabix -p vcf -f input.vcf.gz  ## this command will produce input.vcf.gz.tbi
+
   tabix -p vcf -f input.vcf.gz  ## this command will generate input.vcf.gz.tbi
 
* Even with the presence of VCF file, PED/DAT files are still needed for covariates and phenotypes.
 
* Even with the presence of VCF file, PED/DAT files are still needed for covariates and phenotypes.
  
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