Changes

Shuang's research focuses on the development of statistical methods and tools for the identification and study of genetic variants influencing human disease. Under the lead of professor Gonçalo Abecasis, software that have been developed and released to public are:

Shuang's research focuses on the development of statistical methods and tools for the identification and study of genetic variants influencing human disease. Under the lead of professor Gonçalo Abecasis, software that have been developed and released to public are:

[[Rarefy|'''rarefy''']] is a tool to help selecting informative families and individuals from a sample. It takes account pedigree structure and calculates an informative score for each individual to evaluate the potential of carrying trait-influencing rare variants. It has been used for selecting individuals in Minnesota Twins substance abuse whole-genome sequencing project and SardiNia deep sequencing project.  

*[[Rarefy|'''rarefy''']] is a tool to help selecting informative families and individuals from a sample. It takes account pedigree structure and calculates an informative score for each individual to evaluate the potential of carrying trait-influencing rare variants. It has been used for selecting individuals in Minnesota Twins substance abuse whole-genome sequencing project and SardiNia deep sequencing project.  

[[FamRvTest|'''famRvTest''']] is an efficient tool for rare variant association analysis. It handles related individuals and study specific covariates. The tool supports both single variant and gene-level associations with various methods implemented. It has been used in eQTL and quantitative traits association analyses in T2Dgenes project.

*[[FamRvTest|'''famRvTest''']] is an efficient tool for rare variant association analysis. It handles related individuals and study specific covariates. The tool supports both single variant and gene-level associations with various methods implemented. It has been used in eQTL and quantitative traits association analyses in T2Dgenes project.

[[RAREMETALWORKER|'''raremetalworker''']] is a tool to generate summary statistics for meta-analysis of rare variants using raremetal. It handles both related and unrelated individuals. It has been used in tens of research centers and institutions around the world since its first release in 2012.

*[[RAREMETALWORKER|'''raremetalworker''']] is a tool to generate summary statistics for meta-analysis of rare variants using raremetal. It handles both related and unrelated individuals. It has been used in tens of research centers and institutions around the world since its first release in 2012.

[[RAREMETAL|'''raremetal''']] is a tool for meta-analysis of rare variants. It supports both single variant and gene-level tests. It is currently being used in Exomechip blood lipids consortium and [[EMADS|EMADS]].

*[[RAREMETAL|'''raremetal''']] is a tool for meta-analysis of rare variants. It supports both single variant and gene-level tests. It is currently being used in Exomechip blood lipids consortium and [[EMADS|EMADS]].