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Line 36: Line 36:  
ylab=expression(paste("Observed (",-log[10], " p-value)")),  
 
ylab=expression(paste("Observed (",-log[10], " p-value)")),  
 
draw.conf=TRUE, conf.points=1000, conf.col="lightgray", conf.alpha=.05,
 
draw.conf=TRUE, conf.points=1000, conf.col="lightgray", conf.alpha=.05,
already.transformed=FALSE, pch=20, aspect="iso",  
+
already.transformed=FALSE, pch=20, aspect="iso", prepanel=prepanel.qqunif,
 
par.settings=list(superpose.symbol=list(pch=pch)), ...) {
 
par.settings=list(superpose.symbol=list(pch=pch)), ...) {
 
 
Line 46: Line 46:  
stop("pvalue vector is not numeric, can't draw plot")
 
stop("pvalue vector is not numeric, can't draw plot")
 
if (any(is.na(unlist(pvalues)))) stop("pvalue vector contains NA values, can't draw plot")
 
if (any(is.na(unlist(pvalues)))) stop("pvalue vector contains NA values, can't draw plot")
if (any(unlist(pvalues)==0)) stop("pvalue vector contains zeros, can't draw plot")
+
if (already.transformed==FALSE) {
 
+
if (any(unlist(pvalues)==0)) stop("pvalue vector contains zeros, can't draw plot")
 +
} else {
 +
if (any(unlist(pvalues)<0)) stop("-log10 pvalue vector contains negative values, can't draw plot")
 +
}
 
 
 
 
Line 117: Line 120:  
gc()
 
gc()
 
 
prepanel.origin = function(x,y,...) {
+
prepanel.qqunif= function(x,y,...) {
 
A = list()
 
A = list()
 
A$xlim = range(x, y)*1.02
 
A$xlim = range(x, y)*1.02
Line 127: Line 130:  
#draw the plot
 
#draw the plot
 
xyplot(pvalues~exp.x, groups=grp, xlab=xlab, ylab=ylab, aspect=aspect,
 
xyplot(pvalues~exp.x, groups=grp, xlab=xlab, ylab=ylab, aspect=aspect,
prepanel=prepanel.origin, scales=list(axs="i"), pch=pch,
+
prepanel=prepanel, scales=list(axs="i"), pch=pch,
 
panel = function(x, y, ...) {
 
panel = function(x, y, ...) {
 
if (draw.conf) {
 
if (draw.conf) {

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