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, 18:06, 20 February 2014
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| Sensitivity 0.2% | | Sensitivity 0.2% |
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− | Ins/Del ratios: Reference alignment based methods tend to be biased towards the detection of deletions. This provides a useful measure for discovery Indel sets to show the varying degree of biasness. | + | Ins/Del ratios: Reference alignment based methods tend to be biased towards the detection of deletions. This provides a useful measure for discovery Indel sets to show the varying degree of biasness. It also appears that as coverage increases, the ins/del ratio tends to 1. |
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| Coding region analysis: Coding region Indels may be categorised as Frame shift Indels and Non frameshift Indels. A lower proportion of Frameshift Indels may indicate a better quality data set but this depends also on the individuals sequenced. | | Coding region analysis: Coding region Indels may be categorised as Frame shift Indels and Non frameshift Indels. A lower proportion of Frameshift Indels may indicate a better quality data set but this depends also on the individuals sequenced. |