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A: [[Rare-Metal-Worker|'''RAREMETALWORKER''']] is the program that generates summary statistics for individual studies to share. It generates both single variant association results and covariance matrices of score statistics together with QC statistics. It enables analysis of familial data, population data, unrelated individuals and samples with cryptic relatedness and population stratification. [[RareMETAL|'''RAREMETAL''']] takes the summary statistics generated by RAREMETALWORKER to perform both single variant and gene-level association analysis.