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RAREMETAL METHOD

113 bytes removed, 21:11, 8 April 2014
SINGLE VARIANT META ANALYSIS
===SINGLE VARIANT META ANALYSIS===
Single variant meta-analysis score statistic can be reconstructed from score statistics and their variances generate by each study, assuming unrelated samples across studies, and asymptotically follows standard normal distribution
<math>T_i=\sum_{k=1}^S {U_{i,k}}\bigg/\sqrt{\sum_{k=1}^S{V_{ii,k}}} \sim\mathbf{N}(0,1)</math>
This score statistics asymptotically follows standard normal distribution, or <math>TT_i=\sum_{k=1}^S {U_{i,k}}\bigg/\sqrt{\sum_{k=1}^S{V_{ii,k}}} \sim\mathbf{N}(0,1)</math>
===BURDEN META ANALYSIS===
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