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RAREMETAL METHOD

4 bytes added, 23:19, 8 April 2014
SKAT META ANALYSIS
===SKAT META ANALYSIS===
SKAT has been is most powerful when detecting genes with rare variants having opposite directions in effect sizes. Meta-analysis statistic can also be re-constructed using single variant meta-analysis scores and their covariances
<math>\mathbf{Q}=\mathbf{{U_{meta}}^T}\mathbf{W}\mathbf{U_{meta}}</math>.
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