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, 11:05, 11 April 2013
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| === Estimation of Genotype Frequencies without assuming HWE === | | === Estimation of Genotype Frequencies without assuming HWE === |
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− | We propose an EM algorithm to estimate the genotype frequencies without assuming HWE. The posterior probability of the genotype given the reads for individual k ($R_k$) for the $l$th iteration is given by: \\ | + | We propose an EM algorithm to estimate the genotype frequencies without assuming HWE. The posterior probability of the genotype given the reads for individual k (<math>R_k</math>) for the <math>l</math>th iteration is given by: |
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| <math> | | <math> |