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Revision as of 08:15, 23 October 2017
, 08:15, 23 October 2017Created page with "== Objective == This lecture introduces modern methods for haplotype estimation, which based on an idea introduced by Na Li and Matthew Stephens in 2003. This approach models..."
== Objective ==
This lecture introduces modern methods for haplotype estimation, which based on an idea introduced by Na Li and Matthew Stephens in 2003. This approach models each haplotype in the sample as an imperfect mosaic of other haplotypes. It typically favors solutions that involve longer mosaic pieces and where there are fewer mismatches between each haplotype and its template.
== Slides ==
[[Media:666.2017.10_-_Advanced_Haplotype_Estimation.pdf|Slides in PDF Format]]
== Recommended Reading ==
Li and Stephens (2003) ''Genetics'' '''65''':2213-33.
Li et al (2010) ''Genetic Epidemiology'' '''34''':816–34
This lecture introduces modern methods for haplotype estimation, which based on an idea introduced by Na Li and Matthew Stephens in 2003. This approach models each haplotype in the sample as an imperfect mosaic of other haplotypes. It typically favors solutions that involve longer mosaic pieces and where there are fewer mismatches between each haplotype and its template.
== Slides ==
[[Media:666.2017.10_-_Advanced_Haplotype_Estimation.pdf|Slides in PDF Format]]
== Recommended Reading ==
Li and Stephens (2003) ''Genetics'' '''65''':2213-33.
Li et al (2010) ''Genetic Epidemiology'' '''34''':816–34
