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Revision as of 03:38, 4 December 2017
, 03:38, 4 December 2017→Slides
== Overview ==
== Overview ==
Introduces the issues surrounding de novo assembly of complex genomes, with a particular focus on issues related to variant discovery.
Introduces the issues surrounding de novo assembly of complex genomes, with a particular focus on issues related to variant discovery. Also provides a brief overview of the results of Lander and Waterman on contig length.
== Slides ==
== Slides ==
[[Media:666.2012.01.pdf|Slides in PDF Format]]
[[Media:666.2012.01_-_De_Novo_Assembly.pdf|Slides in PDF Format]]
== Recommended Reading ==
== Recommended Reading ==
Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. ''Nature Genetics'' '''44''':226-232
Iqbal Z, Caccamo M, Turner I, Flicek P, McVean G (2012) De novo assembly and genotyping of variants using colored de Bruijn graphs. ''Nature Genetics'' '''44''':226-232
Lander E and Waterman M (1988) Genomic mapping by fingerprinting random clones: a mathematical analysis. ''Genomics'' '''2''':231-239
