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== Scheduling ==
 
== Scheduling ==
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Professor Hyun Min Kang is currently (Fall 2013) teaching this course.
      
Final grades will take into account performance in written in-class assessments, take home problem sets, as well as participation in class and any class projects.
 
Final grades will take into account performance in written in-class assessments, take home problem sets, as well as participation in class and any class projects.
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== Class Notes ==
 
== Class Notes ==
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[[Biostatistics 666: Contemporary Human Genetics]] - [[Media:|PDF]]
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[[Biostatistics 666: Contemporary Human Genetics]] - [[Media:666.2017.01 - Introductory Lecture.pdf|PDF]]
    
[[Biostatistics 666: Hardy-Weinberg Equilibrium]] - [[Media:666.2017.02 - Hardy Weinberg Equilibrium.pdf|PDF]]
 
[[Biostatistics 666: Hardy-Weinberg Equilibrium]] - [[Media:666.2017.02 - Hardy Weinberg Equilibrium.pdf|PDF]]
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[[Biostatistics 666: Linkage Disequilibrium]] - [[Media:666.03.pdf|PDF]]
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[[Biostatistics 666: Linkage Disequilibrium]] - [[Media:666.2017.03 - Linkage Disequilibrium.pdf|PDF]]
 +
 
 +
[[Biostatistics 666: Introduction to the Coalescent]] - [[Media:666.04 - The Coalescent.pdf|PDF]]
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[[Biostatistics 666: Modeling Variation in the Coalescent]] - [[Media:666.2017.05_-_Coalescent_and_Allele_Counts.pdf|PDF]]
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[[Biostatistics 666: Modeling Recombination and Migration in the Coalescent]] - [[Media:666.2017.06_-_More_Advanced_Coalescent_Models.pdf|PDF]]
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[[Biostatistics 666: Introduction to the Coalescent]] - [[Media:666.04.pdf|PDF]]
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[[Biostatistics 666: Maximum Likelihood Allele Frequency Estimation]] - [[Media:666.2017.07 - Maximum Likelihood Estimation.pdf|PDF]]
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[[Biostatistics 666: Modeling Variation in the Coalescent]] - [[Media:666.05.pdf|PDF]]
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[[Biostatistics 666: Introduction to the E-M Algorithm]] - [[Media:666.2017.08 - The E-M Algorithm.pdf|PDF]]
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[[Biostatistics 666: Modeling Recombination and Migration in the Coalescent]] - [[Media:666.06.pdf|PDF]]
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[[Biostatistics 666: Haplotype Estimation]] - [[Media:666.2017.09_-_Haplotype_Estimation.pdf|PDF]]
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[[Biostatistics 666: Maximum Likelihood Allele Frequency Estimation]] - [[Media:666.09.pdf|PDF]]
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[[Biostatistics 666: Advanced Haplotype Estimation]] - [[Media:666.2017.10_-_Advanced_Haplotyping.pdf|PDF]]
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[[Biostatistics 666: Introduction to the E-M Algorithm]] - [[Media:666.10.pdf|PDF]]
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[[Biostatistics 666: Power of Genomewide Association Studies]] - [[Media:666.2010.01_-_Power_of_Genomewide_Studies.pdf |PDF]]
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[[Biostatistics 666: Haplotype Estimation]] - [[Media:666.11.pdf|PDF]]
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Biostatistics 666: Kinship Coefficients and Relatedness - [[Media:666.2017.12_-_Kinship_Coefficients.pdf|PDF]]
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[[Biostatistics 666: Variance Component Analyses]] - [[Media:666.2017.13_-_Variance_Component_Models.pdf|PDF]]
 +
 
 +
[[Biostatistics 666: Linkage Analysis in Sibling Pairs]] - [[Media:666.2017.14_-_Affected_Sibling_Pairs.pdf|PDF]]
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[[Biostatistics 666: Genotype Imputation]] - [[Media:666.2017.15_-_Genotype_Imputation.pdf|PDF]]
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Lectures below have not yet been updated for 2017.
    
[[Biostatistics 666: Haplotype Association Tests]] - [[Media:666.12.pdf|PDF]]
 
[[Biostatistics 666: Haplotype Association Tests]] - [[Media:666.12.pdf|PDF]]
    
[[Biostatistics 666: Association Tests in Structured Populations]] - [[Media:666.13.pdf|PDF]]
 
[[Biostatistics 666: Association Tests in Structured Populations]] - [[Media:666.13.pdf|PDF]]
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[[Biostatistics 666: Power of Genomewide Association Studies]] - [[Media:666.2010.01.pdf|PDF]]
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[[Biostatistics 666: Linkage Analysis in Sibling Pairs]] - [[Media:666.2010.02.pdf|PDF]]
      
[[Biostatistics 666: Multipoint Analysis in Sibling Pairs]] - [[Media:666.16.pdf|PDF]]
 
[[Biostatistics 666: Multipoint Analysis in Sibling Pairs]] - [[Media:666.16.pdf|PDF]]
    
[[Biostatistics 666: Relationship Checking]] - [[Media:666.17.pdf|PDF]]
 
[[Biostatistics 666: Relationship Checking]] - [[Media:666.17.pdf|PDF]]
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[[Biostatistics 666: Genotype Imputation]] - [[Media:666.2010.03.pdf|PDF]]
      
[[Biostatistics 666: Whole Genome Sequencing]] - [[Media:666.2010.04.pdf|PDF]]
 
[[Biostatistics 666: Whole Genome Sequencing]] - [[Media:666.2010.04.pdf|PDF]]
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[[Biostatistics 666: Rare Variant Burden Tests]] - [[Media:666.2011.01.pdf|PDF]]
 
[[Biostatistics 666: Rare Variant Burden Tests]] - [[Media:666.2011.01.pdf|PDF]]
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[[Biostatistics 666: Variance Component Analyses]] - [[Media:666.20.pdf|PDF]]
      
[[Biostatistics 666: Likelihood Calculations for Large Pedigrees]] - [[Media:666.24.pdf|PDF]]
 
[[Biostatistics 666: Likelihood Calculations for Large Pedigrees]] - [[Media:666.24.pdf|PDF]]
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These lectures were used in previous years, but have been replaced in the most recent edition of the course.
 
These lectures were used in previous years, but have been replaced in the most recent edition of the course.
 +
 +
[[Biostatistics 666: Introductory Lecture]] - [[Media:666.01.pdf|PDF]]
    
[[Biostatistics 666: Course Introduction and Hardy Weinberg Equilibrium]] - [[Media:2011.666.01.pdf|PDF]]
 
[[Biostatistics 666: Course Introduction and Hardy Weinberg Equilibrium]] - [[Media:2011.666.01.pdf|PDF]]
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[[Biostatistics 666: Applications of the Lander-Green Algorithm]] - [[Media:666.19.pdf|PDF]]
 
[[Biostatistics 666: Applications of the Lander-Green Algorithm]] - [[Media:666.19.pdf|PDF]]
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 +
== Problem Sets ==
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[[Media:666.Worksheet 1.pdf|Problem Set 1]] -- [[Media:666.Worksheet_1.Solution.pdf|Solution]]
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[[Media:666.Worksheet_2.pdf|Problem Set 2]] -- [[Media:666.Worksheet_2.Solution.pdf|Solution]]
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[[Media:666.Worksheet_3.pdf|Problem Set 3]] -- [[Media:666.Worksheet_3.Solution.pdf|Solution]]
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[[Media:666.Worksheet_4.pdf|Problem Set 4]]
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[[Media:666.Worksheet_5.pdf|Problem Set 5]]
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== Sample Mid-Term ==
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 +
[[Media:666.SampleMidterm.pdf|Sample Mid-Term]]
    
== Office Hours ==
 
== Office Hours ==
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For the 2012 Fall Term, office hours will take place in office 4614 in the School of Public Health Tower. I will provide free coffee to anyone who turns up.
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For the 2017 Fall Term, office hours are tentatively schedule for Friday afternoons at 3pm. I will provide free coffee to anyone who turns up.
    
== Standards of Academic Conduct ==
 
== Standards of Academic Conduct ==
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* 2011/2012
 
* 2011/2012
 
* 2012/2013
 
* 2012/2013
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* 2017/2018
   −
He last taught it in the 2012/2013 academic year. For previous course notes, see [[http://www.sph.umich.edu/csg/abecasis/class Goncalo's older class notes]].
+
He last taught it in the 2017/2018 academic year. For previous course notes, see [[http://csg.sph.umich.edu/abecasis/class Goncalo's older class notes]].

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