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Revision as of 04:57, 9 February 2010
, 04:57, 9 February 2010Created page with '== Objective == This lecture examines maximum likelihood based estimation of allele frequencies in several simple settings, such as estimation of allele frequencies from samples…'
== Objective ==
This lecture examines maximum likelihood based estimation of allele frequencies in several simple settings, such as estimation of allele frequencies from samples of unrelated individuals and from samples of mother-child pairs. The objective is to both provide an intuition to some of the issues involved in allele frequency estimation but also to review the basic principles of maximum likelihood estimation.
== Slides ==
[[666.09.PDF|Slides in PDF format]]
== Recommended Reading ==
For a review of the principles of maximum likelihood estimation, see an introductory statistics text, such as:
Garthwaite, Jolliffe, Jones (1995) ''Statistical Inference''. Prentice Hall, Hertfordshire (UK)
This lecture examines maximum likelihood based estimation of allele frequencies in several simple settings, such as estimation of allele frequencies from samples of unrelated individuals and from samples of mother-child pairs. The objective is to both provide an intuition to some of the issues involved in allele frequency estimation but also to review the basic principles of maximum likelihood estimation.
== Slides ==
[[666.09.PDF|Slides in PDF format]]
== Recommended Reading ==
For a review of the principles of maximum likelihood estimation, see an introductory statistics text, such as:
Garthwaite, Jolliffe, Jones (1995) ''Statistical Inference''. Prentice Hall, Hertfordshire (UK)
