From Genome Analysis Wiki
Jump to navigationJump to search
732 bytes added
, 19:11, 6 June 2016
Line 4: |
Line 4: |
| = Introduction = | | = Introduction = |
| DosageConvertor is a C++ tool to convert dosage files (in VCF format) from Minimac3 to ther formats such as MaCH or PLINK. | | DosageConvertor is a C++ tool to convert dosage files (in VCF format) from Minimac3 to ther formats such as MaCH or PLINK. |
− |
| |
− |
| |
| | | |
| = Download = | | = Download = |
| | | |
− | '''VERSION: 1.0.1 !!! (Updated 10.25.2015) !!!''' | + | '''VERSION: 1.0.2 !!! (Updated 6.6.2016) !!!''' |
| | | |
− | '''Github Repo:''' Users can clone from github repository as well : [https://github.com/Santy-8128/m3vcftools m3vcftools Github] | + | '''Github Repo:''' Users can clone from github repository as well : [https://github.com/Santy-8128/DosageConvertor Github] |
| | | |
| '''Cloning from GitHub is recommened so that updates can be easily pulled back !!!''' | | '''Cloning from GitHub is recommened so that updates can be easily pulled back !!!''' |
Line 20: |
Line 18: |
| ! Download Link | | ! Download Link |
| |- | | |- |
− | | m3vcftools Source Files | + | | DosageConvertor Source Files |
− | | [ftp://share.sph.umich.edu/m3vcftools/m3vcftools.v1.0.1.tar.gz UNIX Users ] | + | | |
| + | [ftp://share.sph.umich.edu/minimac3/DosageConvertor/DosageConvertor.v1.0.2.tar.gz UNIX Users ] |
| | | |
| |} | | |} |
Line 27: |
Line 26: |
| = Usage= | | = Usage= |
| | | |
− | Users should follow the following steps to compile '''m3vcftools ''' (if they downloaded the source files). | + | Users should follow the following steps to compile '''DosageConvertor ''' (if they downloaded the source files). |
| | | |
| ## EXTRACT M3VCFTOOLS AND COMPILE | | ## EXTRACT M3VCFTOOLS AND COMPILE |
| | | |
− | tar -xzvf m3vcftools.v1.0.1.tar.gz | + | tar -xzvf DosageConvertor.v1.0.2.tar.gz |
− | cd m3vcftools / | + | cd DosageConvertor/ |
| make | | make |
| | | |
− | For e.g. to calculate LD the command should be: <code>../bin/m3vcftools --vcf INPUT.m3vcf.gz --hap-r2 --ld-window-bp 10000 --min-r2 0.4 --out PREFIX</code> | + | For e.g. to calculate LD the command should be: <code> |
| + | |
| + | Usage: ./DosageConvertor --vcfDose TestDataImputedVCF.dose.vcf.gz |
| + | --info TestDataImputedVCF.info |
| + | --prefix OutputFilePrefix |
| + | --type plink OR mach // depending on output format |
| + | --format DS or GP // based on if you want to output |
| + | // dosage (DS) or genotype prob (GP) |
| + | --buffer 10000 // Number of Markers to import and |
| + | // print at a time (valid only for |
| + | // MaCH format) |
| + | --idDelimiter _ // Delimiter to Split VCF Sample ID into |
| + | // FID and IID for PLINK format |
| + | </code> |
| | | |
− | For e.g. to convert a VCF file into M3VCF format : <code>../bin/m3vcftools --vcf INPUT.vcf.gz --recode --out PREFIX</code>
| |
| | | |
| = Contact = | | = Contact = |
| | | |
| In case of any queries and bugs please contact [mailto:sayantan@umich.edu Sayantan Das]. | | In case of any queries and bugs please contact [mailto:sayantan@umich.edu Sayantan Das]. |