Changes

From Genome Analysis Wiki
Jump to navigationJump to search
309 bytes added ,  11:54, 18 September 2012
no edit summary
Line 24: Line 24:  
== 3.  Prepare PED file for phenotypes and covariates  ==
 
== 3.  Prepare PED file for phenotypes and covariates  ==
   −
EPACTS accepts the PED format supported by MERLIN or PLINK to represent the phenotypes and covariates.  You may prepare either (1) a PED file without column headers + accompanying DAT file, or (2) a PED file with column headers.
+
EPACTS accepts the PED format supported by MERLIN or [http://pngu.mgh.harvard.edu/~purcell/plink/data.shtml PLINK ]to represent the phenotypes and covariates.  You may prepare either (1) a PED file without column headers + accompanying DAT file, or (2) a PED file with column headers.  The standard PED format has 6 mandatory columns:
 +
 
 +
#Family ID
 +
#Individual ID
 +
#Paternal ID
 +
#Maternal ID
 +
#Sex (1=male; 2=female; other=unknown)
 +
#Phenotype
 +
 
 +
Columns 7 and onwards are covariate information.  For example
 +
 
 +
#AGE
 +
#SEX
 +
#PC1
 +
#PC2
 +
 
 +
etc.
216

edits

Navigation menu