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Association Analysis
Association Analysis
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Statistical Test
Statistical Test
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Subset of SNPs
Subset of SNPs
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Output File Type
Output File Type
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Output Filename Format
Output Filename Format
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A. Typical DIAGRAM analysis using existing association pipeline
A. Typical DIAGRAM analysis using existing association pipeline
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Wald or likelihood ratio
Wald or likelihood ratio
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All SNPs with min MAC >= 1
All SNPs with min MAC >= 1
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Custom file based on DIAGRAM format
Custom file based on DIAGRAM format
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DIAGRAMv4_QQQ_XXX_1000G_KKK_YYY_ZZZ.txt
DIAGRAMv4_QQQ_XXX_1000G_KKK_YYY_ZZZ.txt
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B. Analysis of all SNPs using logistic regression score test
B. Analysis of all SNPs using logistic regression score test
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Score test
Score test
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All SNPs with min MAC >= 1
All SNPs with min MAC >= 1
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EPACTS output file
EPACTS output file
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DIAGRAMv4_QQQ_XXX_1000G_KKK_SCR_YYY_ZZZ.epacts
DIAGRAMv4_QQQ_XXX_1000G_KKK_SCR_YYY_ZZZ.epacts
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C. Analysis of low frequency variants using Firth bias-corrected logistic regression
C. Analysis of low frequency variants using Firth bias-corrected logistic regression
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Firth bias-corrected
Firth bias-corrected
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SNPs with 200 >= MAC >= 1
SNPs with 200 >= MAC >= 1
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EPACTS output file
EPACTS output file
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DIAGRAMv4_QQQ_XXX_1000G_KKK_FIR_YYY_ZZZ.epacts
DIAGRAMv4_QQQ_XXX_1000G_KKK_FIR_YYY_ZZZ.epacts
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=== A. Typical DIAGRAM analysis using existing association pipeline<br> ===
=== A. Typical DIAGRAM analysis using existing association pipeline<br> ===
