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In this case, sequencing 8 individuals would provide information on 13 genomes.
In this case, sequencing 8 individuals would provide information on 13 genomes.
== Improvements Under Consideration ==
* Change sorting so that the most valuable individuals for each pedigree are picked first. When resources are limited, it might not be affordable to sequence enough individuals to completely impute each pedigree. This scoring order would allow one to more easily focus on the highest value individuals in each pedigree.
* Implement the ability to evaluate only nuclear families, ignoring the possibility of imputing more distant relatives.
* Add the summed number of sequenced or imputed affecteds to the per family output.
* Unrelated single individuals (''founders'' without offspring) are currently scored as zero value. These should more accurately be scored as single genomes.
== Acknowledgements ==
== Acknowledgements ==
Weimin Chen and Serena Sanna for discussions that contributed to the initial version of this program. John Blangero at the Southwest Foundation for testing initial version.
Weimin Chen and Serena Sanna for discussions that contributed to the initial version of this program. John Blangero at the Southwest Foundation for testing initial version.
