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== Splice Variants ==

== Splice Variants ==

We tallied 43,702 splice variants seen at least once across ~12,000 sequenced samples. Among these splice variants, the majority were seen only once (26,847). Of the remaining variants (16,855), a total of 12,459 were seen in at least 2 datasets and are considered as candidates for inclusion in exome SNP arrays. The transition transversion ratio of this class of variants was XXX for variants in dbSNP 132 and XXX for non dbSNP variants.

We tallied 44,529 splice variants seen at least once across ~12,000 sequenced samples. Among these splice variants, the majority were seen only once (27,265). Of the remaining variants (17,264), a total of 12,662 were seen in at least 2 datasets and are considered as candidates for inclusion in exome SNP arrays. The transition transversion ratio of this class of variants was 2.13 for all variants and 2.94 for variants that met criteria for inclusion in these arrays (being seen 2 or more times and in 2 or more studies).

These variants include %%% of the XXX stop altering variants detected in average genome through exome sequencing.

We estimate the candidate list of variants includes 94-95% of the stop altering variants detected in an average genome through exome sequencing.

== Stop Altering Variants ==

== Stop Altering Variants ==