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, 18:43, 29 September 2011
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| == Scaffold for Identity by Descent == | | == Scaffold for Identity by Descent == |
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− | We selected a grid of 5,805 markers (distributed approximately one per 500 kb across the autosomes and the X chromosome) that showed little differentiation between African-, European- and Asian-ancestry sequenced by the 1000 Genomes Project and allele frequency close to 0.50. Markers previously genotyped on the Illumina Omni 2.5M array were favored and markers with A/T or G/C alleles were avoided. | + | We selected a grid of 5,710 markers (distributed approximately one per 500 kb across the autosomes and the X chromosome) that showed little differentiation between African-, European- and Asian-ancestry sequenced by the 1000 Genomes Project and allele frequency close to 0.50. Markers previously genotyped on the Illumina Omni 2.5M array were favored and markers with A/T or G/C alleles were avoided. |
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| These markers can be used to identify stretches of identity by descent between apparently unrelated individuals or to support linkage-based analyses in appropriate family samples. | | These markers can be used to identify stretches of identity by descent between apparently unrelated individuals or to support linkage-based analyses in appropriate family samples. |
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− | In this category, 3,369 markers passed assay design.
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| == Functionally interesting variants == | | == Functionally interesting variants == |