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A general guideline for genotyping calling in families.
A general guideline for genotyping calling in families.
Polymutt: Small to big pedigrees.
Polymutt: Small to big pedigrees, modest to high depth
FamLDCaller/TrioCaller: many small pedigrees, low to modest depths.
FamLDCaller: many small pedigrees, low to modest depths.
FamLDCaller is an extension of [http://genome.sph.umich.edu/wiki/TrioCaller TrioCaller] to handle nuclear and general family structure.
'''Download''':
[[Binary file:]] [http://www.pitt.edu/~wec47/Files/FamLDCaller FamLDCaller]. [Last update: 08/15/2014]
More details will come soon. Please contact Wei Chen at weichen.mich@gmail.com for any questions.
Major updates.
Major updates.
3. More flexible loading functions for VCF files (no need to remove non-SNP variant)
3. More flexible loading functions for VCF files (no need to remove non-SNP variant)
