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, 17:06, 2 September 2013
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| * Go to FamRV_0.0.1/famRvTest/bin and use the following: | | * Go to FamRV_0.0.1/famRvTest/bin and use the following: |
| ./famRvTest | | ./famRvTest |
| + | |
| + | ==Approach== |
| + | '''famRvTest''' uses linear mixed model approach to account for familial relationship, where kinship is either quantified based upon pedigree structures or estimated from genotypes of markers from genome-wide. Single marker associations including score, likelihood ratio and ward tests and gene-level associations methods (weighted and un-weighted burden, SKAT and variable threshold) have been implemented. Manuscript is under preparation. |