Changes

From Genome Analysis Wiki
Jump to navigationJump to search
455 bytes added ,  17:06, 2 September 2013
no edit summary
Line 19: Line 19:  
* Go to FamRV_0.0.1/famRvTest/bin and use the following:
 
* Go to FamRV_0.0.1/famRvTest/bin and use the following:
 
   ./famRvTest
 
   ./famRvTest
 +
 +
==Approach==
 +
'''famRvTest''' uses linear mixed model approach to account for familial relationship, where kinship is either quantified based upon pedigree structures or estimated from genotypes of markers from genome-wide. Single marker associations including score, likelihood ratio and ward tests and gene-level associations methods (weighted and un-weighted burden, SKAT and variable threshold) have been implemented. Manuscript is under preparation.
2,004

edits

Navigation menu