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, 08:01, 21 April 2010
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| == Burden Tests == | | == Burden Tests == |
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− | The same analyses that were originally carried for single variants should be carried out for groups of rare variants. In principle, one could simple use the presence of a rare variant (or a particular class of rare variant, such as a non-synonymous variant or a newly discovered variant) as a predictor and repeat the logistic regression, linear regression or genotype regression described above. For an initial pass, I think the precise form of this analysis is not critical, because the next step is to... | + | The same analyses that were originally carried for single variants should be carried out for groups of rare variants. In principle, one could simply use the presence of a rare variant (or a particular class of rare variant, such as a non-synonymous variant or a newly discovered variant) as a predictor and repeat the logistic regression, linear regression or genotype regression described above. For an initial pass, I think the precise form of this analysis is not critical, because the next step is to... |
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| == More Q-Q Plots == | | == More Q-Q Plots == |