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Revision as of 06:50, 4 June 2010
, 06:50, 4 June 2010→Estimating Model Parameters
== Estimating Model Parameters ==
== Estimating Model Parameters ==
The first step for genotype imputation analyses using MaCH is to build a model that relates your dataset to a reference set of haplotypes. This model will include information on the length of haplotype stretches shared between your sample and the reference panel (in a ''.rec'' file) and information on the similarity of marker genotypes between your sample and the reference panel (in a ''.err'' file). The contents of the second file reflect the combined effects of genotyping error and differences in genotyping assays between the two samples.
