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, 06:41, 26 April 2011
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| Imputing genotypes using '''minimac''' is an easy and straightforward process: after selecting a set of reference haplotypes, plugging-in the target haplotypes from the previous step and setting the number of rounds to use for the model parameter estimation, imputation should proceed rapidly. | | Imputing genotypes using '''minimac''' is an easy and straightforward process: after selecting a set of reference haplotypes, plugging-in the target haplotypes from the previous step and setting the number of rounds to use for the model parameter estimation, imputation should proceed rapidly. |
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| + | === Creating SNP List File === |
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| + | '''Minimac''' requires a file listing markers in the haplotype file. This file can be easily generated by extracting the first column from the .info file created during the MaCH haplotyping process. In a standard Unix system, a command like this should do: |
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| + | cut -f 1 target.info > target.snps |
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| === Running Minimac === | | === Running Minimac === |