From Genome Analysis Wiki
Jump to navigationJump to search
964 bytes added
, 00:20, 29 January 2015
Line 28: |
Line 28: |
| = Usage= | | = Usage= |
| | | |
| + | Users should follow the following steps to compile Minimac3 (if they downloaded the source files) or should skip them (if they downloaded the binary executable). |
| + | |
| + | ## EXTRACT MINIMAC3 AND COMPILE |
| + | |
| + | tar -xzvf Minimac3.v1.0.0.tar.gz |
| + | cd Minimac3/ |
| + | make |
| + | |
| + | A typical Minimac3 command line for imputation is as follows |
| + | |
| + | ../bin/Minimac3 --refHaps refPanel.vcf \ |
| + | --haps targetStudy.vcf \ |
| + | --prefix testRun |
| + | |
| + | Here <code>refPanel.vcf</code> is the reference panel used in VCF format (e.g. 1000 Genomes), <code>targetStudy.vcf</code> is the phased GWAS data in VCF format and <code>testRun</code> is the prefix for the output files. Some commonly used reference panels are available for download in [[#Reference Panels for Download| Reference Panels]]. See wiki page on [[Minimac3 Usage| Detailed Usage]] and [[Minimac3 Imputation Cookbook|Imputation Cookbook]] for further details on using '''Minimac3''' for imputation analysis. |
| + | |
| Users can always type the following for further support: | | Users can always type the following for further support: |
| | | |