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984 bytes added ,  10:39, 11 April 2014
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* --noeof allows using VCF file without BGZF EOF markers. This is a very rare option to use. If your run is terminated with error message: "", then you might want to check out this option.
 
* --noeof allows using VCF file without BGZF EOF markers. This is a very rare option to use. If your run is terminated with error message: "", then you might want to check out this option.
   −
=== Output Format===
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=== RAREMETAWORKER OUTPUT===
   −
* There are three files generated automatically by default:
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====OUTPUT FILE NAMES====
   −
   prefix.traitName.singlevar.score.txt
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* Three files are generated automatically by default:
   prefix.traitName.singlevar.cov.txt
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  prefix.traitName.singlevar.score.txt (single variant summary statistics and QC statistics)
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  prefix.traitName.singlevar.cov.txt (covariance matrices of single variant score statistics)
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  prefix.singlevar.log (log file)
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* If --zip option is used, then the following will be generated automatically:
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   prefix.traitName.singlevar.score.txt.gz
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   prefix.traitName.singlevar.cov.txt.gz
 
   prefix.singlevar.log
 
   prefix.singlevar.log
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* prefix.traitName.singlevar.score.txt contains summary statistics that are needed by Rare-Metal. An example is shown in below:
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* If --recessive and/or --dominant options are used, then the following files are also generated '''in addition''' to the above files
 +
  prefix.traitName.recessive.singlevar.score.txt.gz
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  prefix.traitName.recessive.singlevar.cov.txt.gz
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  prefix.traitName.dominant.singlevar.score.txt.gz
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  prefix.traitName.dominant.singlevar.cov.txt.gz
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* If --kinGeno --kinSave is used, then the genomic relationship matrix is stored in
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  prefix.Empirical.Kinship.gz
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* If --vcX option is used, then the genomic relationship matrix from chromosome X is stored in
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  prefix.Empirical.KinshipX.gz
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====OUTPUT FILE FORMATS====
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* In the file with summary statistics named prefix.traitName.singlevar.score.txt contains summary statistics that are needed by Rare-Metal. An example is shown in below:
    
   LDL mean= -0.00, variance=  1.00, heritability= 34.30
 
   LDL mean= -0.00, variance=  1.00, heritability= 34.30
2,004

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