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| * --makeResiduals can be combined with --useCovariates to generate residuals from a simple linear regressions before analysis. If the --inverseNormal option is also used, then the residuals will be quantile normalized before fitting variance component model. | | * --makeResiduals can be combined with --useCovariates to generate residuals from a simple linear regressions before analysis. If the --inverseNormal option is also used, then the residuals will be quantile normalized before fitting variance component model. |
| ** An example Command line requesting pre-adjustment for covariates before fitting a variance component follows: | | ** An example Command line requesting pre-adjustment for covariates before fitting a variance component follows: |
− | --useCovariates --makeResiduals --inverseNormal | + | --makeResiduals --inverseNorma |
− | ** An example command line requesting joint modeling of fixed effects and variance components follows:
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− | --useCovariates --inverseNormal
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| * If --inverseNormal is used WITHOUT --makeResiduals, then trait values are inverse normalized before any model fitting. | | * If --inverseNormal is used WITHOUT --makeResiduals, then trait values are inverse normalized before any model fitting. |
| * --traitName is created for situations when you have many traits saved in your PED and DAT file, but you are interested in one or a few of them. It can read a file ending with .txt with each trait of interest in a separate line, or trait names separated with "/". An example to handle one trait or multiple traits is in the following: | | * --traitName is created for situations when you have many traits saved in your PED and DAT file, but you are interested in one or a few of them. It can read a file ending with .txt with each trait of interest in a separate line, or trait names separated with "/". An example to handle one trait or multiple traits is in the following: |