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, 17:53, 16 March 2018
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| + | [[Category:RAREMETAL]] |
| ==Useful Pages== | | ==Useful Pages== |
| * The [[RAREMETAL| Home Page]] | | * The [[RAREMETAL| Home Page]] |
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| | | |
| === Association Methods for Meta-analysis === | | === Association Methods for Meta-analysis === |
− | --useExact [ON|OFF] | + | --useExact optimized method for unbalanced studies with unrelated samples, |
− | --burden [ON|OFF] | + | described [[RAREMETAL METHOD#SINGLE_VARIANT_SCORE_TEST]]. |
− | --MB [ON|OFF] | + | --burden burden test with equal weight |
− | --VT [ON|OFF] | + | --MAB burden test with MAF as weight |
− | --SKAT [ON|OFF] | + | --MB burden test with sqrt(maf(1-maf)) as weight |
| + | --BBeta beta distribution as weight |
| + | --VT variant threshold test |
| + | --SKAT standard SKAT test |
| --condition [your.list.of variants.to.be.conditioned.upon] | | --condition [your.list.of variants.to.be.conditioned.upon] |
| Additional details for these options are [[Rare-Metal#Association_Methods|available]]. | | Additional details for these options are [[Rare-Metal#Association_Methods|available]]. |