Changes

=== Generate a VCF File to Annotate Outside of Rare Metal ===

=== Generate a VCF File to Annotate Outside of Rare Metal ===

* --writeVCF allows user to write a VCF file including pooled single variants from all studies. Then users can use their favorite annotation tool to annotate the VCF file. After annotating the VCF file, users can use that file as input for '''rareMETAL''' for further gene-based or region-based meta analysis.

* --writeVCF allows user to write a VCF file including pooled single variants from all studies. Then users can use their favorite annotation tool to annotate the VCF file. After annotating the VCF file, users can use that file as input for '''RAREMETAL''' for further gene-based or region-based meta analysis.

* The output vcf file will be name as: yourPrefix.pooled.variants.vcf. An example output vcf file is in the following:

* The output vcf file will be name as: yourPrefix.pooled.variants.vcf. An example output vcf file is in the following:

   #CHROM    POS    ID      REF    ALT    QUAL    FILTER  INFO

   #CHROM    POS    ID      REF    ALT    QUAL    FILTER  INFO