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, 21:10, 8 April 2014
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| ===SINGLE VARIANT META ANALYSIS=== | | ===SINGLE VARIANT META ANALYSIS=== |
| Single variant meta-analysis score statistic can be reconstructed from score statistics and their variances generate by each study, assuming unrelated samples across studies, and is written | | Single variant meta-analysis score statistic can be reconstructed from score statistics and their variances generate by each study, assuming unrelated samples across studies, and is written |
− | <math>T_i=\sum_{k=1}^S {U_{i,k}}\bigg/\sqrt{\sum_{k=1}^S{V_{ii,k}}}</math> | + | <math>T_i=\sum_{k=1}^S {U_{i,k}}\bigg/\sqrt{\sum_{k=1}^S{V_{ii,k}}}</math>. |
− | The score statistics asymptotically follows standard normal distribution, or <math>T\sim\mathbf{N}(0,1)</math>
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| + | This score statistics asymptotically follows standard normal distribution, or <math>T\sim\mathbf{N}(0,1)</math> |
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| ===BURDEN META ANALYSIS=== | | ===BURDEN META ANALYSIS=== |