From Genome Analysis Wiki
Jump to navigationJump to search
83 bytes added
, 12:07, 17 July 2016
Line 15: |
Line 15: |
| * solve the numeric issue of lambda = 0 in SKAT | | * solve the numeric issue of lambda = 0 in SKAT |
| * In conditional analysis, when cov matrix between the test variant and its conditioned variants is not invertible, MathSVD still tries to invert that matrix and that leads to weird conditional p values. | | * In conditional analysis, when cov matrix between the test variant and its conditioned variants is not invertible, MathSVD still tries to invert that matrix and that leads to weird conditional p values. |
| + | * '''Optimization for unbalanced studies''' |
| + | * '''Optimization for binary traits''' |