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| VTYPE is [AifZH] for SAM and [AcCsSiIfZH]
| VTYPE is [AifZH] for SAM and [AcCsSiIfZH] for BAM
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| For TAG = E2, length should be the same as the Read Length
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| For TAG = E2, each base should be different than the read Base (unless 'N')
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| For TAG = U2, length should be the same as the Read Length
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