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, 08:30, 11 September 2017
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| == Objective == | | == Objective == |
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− | The objective of this lecture is to introduce the concept of Hardy Weinberg equilibrium. Hardy Weinberg equilibrium is a property of genetic data that allows us to parsimoniously describe genotype frequencies in a population. The reasons why Hardy Weinberg equilibrium generally holds, common reasons for deviation from Hardy Weinberg equilibrium, and methods for checking for significant deviations from Hardy-Weinberg equilibrium. | + | The objective of this lecture is to introduce the concept of Hardy Weinberg equilibrium. Hardy Weinberg equilibrium is a property of genetic data that allows us to parsimoniously describe genotype frequencies in a population. The reasons why Hardy Weinberg equilibrium generally holds, common reasons for deviation from Hardy Weinberg equilibrium, and methods for checking for significant deviations from Hardy-Weinberg equilibrium will all be discussed. |
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| == Slides == | | == Slides == |
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− | [[Media:666.02.pdf|Slides in PDF Format]] | + | [[Media:666.2017.02 - Hardy Weinberg Equilibrium.pdf|Slides in PDF format]] |
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| + | [[Media:666.02.pdf|Previous version]] |
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| == Background Reading == | | == Background Reading == |
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| Wigginton JE, Cutler DJ and Abecasis GR (2005). A note on exact tests of Hardy-Weinberg equilibrium. ''Am J Hum Genet'' '''76''':887-93 | | Wigginton JE, Cutler DJ and Abecasis GR (2005). A note on exact tests of Hardy-Weinberg equilibrium. ''Am J Hum Genet'' '''76''':887-93 |
| + | [http://www.sph.umich.edu/csg/abecasis/publications/15789306.html Abstract and PDF] |