Test EPACTS for DIAGRAM
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Revision as of 21:07, 24 September 2012 by Clement Ma (talk | contribs)
Download EPACTS
EPACTS is available for download here (100Mb) .
Requirements
- Linux 64bit
- Perl vX
- gcc vX
Install EPACTS
Uncompress EPACTS package to the directory you would like to install
tar xzvf epacts_v2_01.noref_binary.2012_07_06.tar.gz
Example
Once installed, test out the software by running a quick example using the test data provided in the "example" directory. The example VCF and PED files are:
${EPACTS_DIRECTORY}/example/1000G_exome_chr20_example_softFiltered.calls.vcf.gz ${EPACTS_DIRECTORY}/example/1000G_dummy_pheno.ped
Run the single variant score test on the example data using this command:
${EPACTS_DIR}/epacts single \ --vcf {EPACTS_DIR}/example/1000G_exome_chr20_example_softFiltered.calls.vcf.gz \ --ped {EPACTS_DIR}/example/1000G_dummy_pheno.ped \ --min-maf 0.001 --chr 20 --pheno DISEASE --cov AGE --cov SEX --test b.score --anno \ --out {OUTPUT_DIR}/test --run 2 &
This command will run the single variant test on the input VCF and PED files, with a minimum MAF threshold of 0.001. The phenotype is "DISEASE" and we are adjusting the analysis with covariates AGE and SEX. The output file directory prefix is {OUTPUT_DIR}/test. Finally, EPACTS will run the analysis in parallel on 2 CPUs.
Expected output