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==Introduction==
 
==Introduction==
In this tutorial, we will show how to run RareMetalWorker and RareMETAL to perform meta analysis using example data sets.
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[http://genome.sph.umich.edu/wiki/Rare-Metal-Worker '''RareMetalWorker'''] is the pre-processing tool to analyze data from individual studies and generate summary statistics for further meta analysis using RareMETAL.
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In this tutorial, we will use RareMetalWorker and RareMetal to perform a simple rare variant meta analysis. [[Rare-Metal-Worker]] is a tool that generates summary statistics that be shared to enable meta-analysis of gene-level association tests. [[Rare-Metal]] uses the files generated by RareMetalWorker as input and produces single variant or gene level association test statistics.
 
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[http://genome.sph.umich.edu/wiki/Rare-Metal#Where_to_Download '''RareMETAL'''] is the tool to do gene-level meta analysis.
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For detailed documentation of both tools, please go to the following:
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  [http://genome.sph.umich.edu/wiki/Rare-Metal-Worker '''RareMetalWorker Documentation''']
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  [http://genome.sph.umich.edu/wiki/Rare-Metal '''RareMETAL Documentation''']
      
==STEP 1: Install Software and Download Example Data Sets==
 
==STEP 1: Install Software and Download Example Data Sets==

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