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, 21:47, 7 March 2013
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| ==Introduction== | | ==Introduction== |
− | In this tutorial, we will show how to run RareMetalWorker and RareMETAL to perform meta analysis using example data sets.
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− | [http://genome.sph.umich.edu/wiki/Rare-Metal-Worker '''RareMetalWorker'''] is the pre-processing tool to analyze data from individual studies and generate summary statistics for further meta analysis using RareMETAL. | + | In this tutorial, we will use RareMetalWorker and RareMetal to perform a simple rare variant meta analysis. [[Rare-Metal-Worker]] is a tool that generates summary statistics that be shared to enable meta-analysis of gene-level association tests. [[Rare-Metal]] uses the files generated by RareMetalWorker as input and produces single variant or gene level association test statistics. |
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− | [http://genome.sph.umich.edu/wiki/Rare-Metal#Where_to_Download '''RareMETAL'''] is the tool to do gene-level meta analysis. | |
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− | For detailed documentation of both tools, please go to the following:
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− | [http://genome.sph.umich.edu/wiki/Rare-Metal-Worker '''RareMetalWorker Documentation''']
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− | [http://genome.sph.umich.edu/wiki/Rare-Metal '''RareMETAL Documentation''']
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| ==STEP 1: Install Software and Download Example Data Sets== | | ==STEP 1: Install Software and Download Example Data Sets== |