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| -I file containing list of intervals [] | | -I file containing list of intervals [] |
| -i intervals | | -i intervals |
| + | -? displays help |
| + | </div> |
| + | </div> |
| + | |
| + | === Estimate === |
| + | |
| + | Compute features in a VCF file. Example of statistics are Allele counts, [[Genotype_Likelihood_based_Inbreeding_Coefficient|Genotype Likelihood based Inbreeding Coefficient]]. |
| + | [[Genotype_Likelihood_based_Allele_Frequency|Hardy-Weinberg Genotype Likelihood based Allele Frequencies]] |
| + | |
| + | <div class=" mw-collapsible mw-collapsed"> |
| + | #compute features for the variants found in vt.vcf |
| + | #requires GT, PL and DP |
| + | vt compute_features vt.vcf |
| + | |
| + | #annotates variants with the following fields |
| + | ##INFO=<ID=AC,Number=A,Type=Integer,Description="Alternate Allele Counts"> |
| + | ##INFO=<ID=AN,Number=1,Type=Integer,Description="Total Number Allele Counts"> |
| + | ##INFO=<ID=NS,Number=1,Type=Integer,Description="Number of Samples With Data"> |
| + | ##INFO=<ID=AF,Number=A,Type=Float,Description="Alternate Allele Frequency"> |
| + | ##INFO=<ID=GC,Number=G,Type=Integer,Description="Genotype Counts"> |
| + | ##INFO=<ID=GN,Number=1,Type=Integer,Description="Total Number of Genotypes Counts"> |
| + | ##INFO=<ID=GF,Number=G,Type=Float,Description="Genotype Frequency"> |
| + | ##INFO=<ID=HWEAF,Number=A,Type=Float,Description="Genotype likelihood based MLE Allele Frequency assuming HWE"> |
| + | ##INFO=<ID=HWEGF,Number=G,Type=Float,Description="Genotype likelihood based MLE Genotype Frequency assuming HWE"> |
| + | ##INFO=<ID=MLEAF,Number=A,Type=Float,Description="Genotype likelihood based MLE Allele Frequency"> |
| + | ##INFO=<ID=MLEGF,Number=G,Type=Float,Description="Genotype likelihood based MLE Genotype Frequency"> |
| + | ##INFO=<ID=HWE_LLR,Number=1,Type=Float,Description="Genotype likelihood based Hardy Weinberg ln(Likelihood Ratio)"> |
| + | ##INFO=<ID=HWE_LPVAL,Number=1,Type=Float,Description="Genotype likelihood based Hardy Weinberg Likelihood Ratio Test Statistic ln(p-value)"> |
| + | ##INFO=<ID=HWE_DF,Number=1,Type=Integer,Description="Degrees of freedom for Genotype likelihood based Hardy Weinberg Likelihood Ratio Test Statistic"> |
| + | ##INFO=<ID=FIC,Number=1,Type=Float,Description="Genotype likelihood based Inbreeding Coefficient"> |
| + | ##INFO=<ID=AB,Number=1,Type=Float,Description="Genotype likelihood based Allele Balance"> |
| + | |
| + | <div class="mw-collapsible-content"> |
| + | usage : vt compute_features for variants [options] <in.vcf> |
| + | |
| + | options : -s print site information only without genotypes [false] |
| + | -o output VCF/VCF.GZ/BCF file [-] |
| + | -f filter expression [] |
| + | -I File containing list of intervals |
| + | -i Intervals |
| -? displays help | | -? displays help |
| </div> | | </div> |