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2,466 bytes added ,  22:00, 7 May 2015
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             -I  file containing list of intervals []
 
             -I  file containing list of intervals []
 
             -i  intervals
 
             -i  intervals
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            -?  displays help
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</div>
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</div>
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=== Estimate ===
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Compute features in a VCF file.  Example of statistics are Allele counts, [[Genotype_Likelihood_based_Inbreeding_Coefficient|Genotype Likelihood based Inbreeding Coefficient]].
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[[Genotype_Likelihood_based_Allele_Frequency|Hardy-Weinberg Genotype Likelihood based Allele Frequencies]]
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<div class=" mw-collapsible mw-collapsed">
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  #compute features for the variants found in vt.vcf
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  #requires GT, PL and DP
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  vt compute_features vt.vcf
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  #annotates variants with the following fields
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  ##INFO=<ID=AC,Number=A,Type=Integer,Description="Alternate Allele Counts">
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  ##INFO=<ID=AN,Number=1,Type=Integer,Description="Total Number Allele Counts">
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  ##INFO=<ID=NS,Number=1,Type=Integer,Description="Number of Samples With Data">
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  ##INFO=<ID=AF,Number=A,Type=Float,Description="Alternate Allele Frequency">
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  ##INFO=<ID=GC,Number=G,Type=Integer,Description="Genotype Counts">
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  ##INFO=<ID=GN,Number=1,Type=Integer,Description="Total Number of Genotypes Counts">
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  ##INFO=<ID=GF,Number=G,Type=Float,Description="Genotype Frequency">
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  ##INFO=<ID=HWEAF,Number=A,Type=Float,Description="Genotype likelihood based MLE Allele Frequency assuming HWE">
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  ##INFO=<ID=HWEGF,Number=G,Type=Float,Description="Genotype likelihood based MLE Genotype Frequency assuming HWE">
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  ##INFO=<ID=MLEAF,Number=A,Type=Float,Description="Genotype likelihood based MLE Allele Frequency">
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  ##INFO=<ID=MLEGF,Number=G,Type=Float,Description="Genotype likelihood based MLE Genotype Frequency">
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  ##INFO=<ID=HWE_LLR,Number=1,Type=Float,Description="Genotype likelihood based Hardy Weinberg ln(Likelihood Ratio)">
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  ##INFO=<ID=HWE_LPVAL,Number=1,Type=Float,Description="Genotype likelihood based Hardy Weinberg Likelihood Ratio Test Statistic ln(p-value)">
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  ##INFO=<ID=HWE_DF,Number=1,Type=Integer,Description="Degrees of freedom for Genotype likelihood based Hardy Weinberg Likelihood Ratio Test Statistic">
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  ##INFO=<ID=FIC,Number=1,Type=Float,Description="Genotype likelihood based Inbreeding Coefficient">
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  ##INFO=<ID=AB,Number=1,Type=Float,Description="Genotype likelihood based Allele Balance">
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<div class="mw-collapsible-content">
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  usage : vt compute_features for variants [options] <in.vcf>
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  options : -s  print site information only without genotypes [false]
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            -o  output VCF/VCF.GZ/BCF file [-]
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            -f  filter expression []
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            -I  File containing list of intervals
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            -i  Intervals
 
             -?  displays help
 
             -?  displays help
 
  </div>
 
  </div>
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