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The imputation quality of both approaches is comparable.  
 
The imputation quality of both approaches is comparable.  
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If you are carrying out only an one-time imputation and you are focusing only on autosomes - then go with MaCH.
+
If you are carrying out only an one-time imputation, using a reference panel with <200 haplotypes and focusing only on autosomes - then go with MaCH.
 
  −
If you are planning to re-impute into new reference panels frequently and/or you are interested into the X-chromosome - then minimac is the right choice for you.
      +
If you are using a large reference panel, planning to re-impute your data as new reference panels become available or interested in X-chromosome imputation - then minimac is the right choice for you.
    
[[Image:Imputation_approaches.png|border]]
 
[[Image:Imputation_approaches.png|border]]
    
[[Image:Time.png|border]]
 
[[Image:Time.png|border]]
      
== Getting Started ==
 
== Getting Started ==

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