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, 09:14, 5 August 2011
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− | This page documents how to impute 1000 Genome SNPs using [[Minimac]], which is typically the preferred approach for imputation using large reference panels such as the 1000 Genomes data. For information on how to carry out 1000 Genomes Imputation using [[MaCH]], see [[MaCH: 1000 Genomes Imputation Cookbook]]. For pointers on how to carry out 1000 Genomes Imputation using [[IMPUTE2]], see [[IMPUTE2: 1000 Genomes Imputation Cookbook]]. | + | This page documents how to impute 1000 Genome SNPs using [[Minimac]], which is typically the preferred approach for imputation using large reference panels such as the 1000 Genomes data. For information on how to carry out 1000 Genomes Imputation using [[MaCH]], see [[MaCH: 1000 Genomes Imputation Cookbook]]. For pointers on how to carry out 1000 Genomes Imputation using [[IMPUTE2]], see [[IMPUTE2: 1000 Genomes Imputation Cookbook]]. |
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| + | Before reading this tutorial, you might find it useful to spend a few minutes reading through the main [[Minimac]] documentation. |
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| == Should I use MaCH or minimac? == | | == Should I use MaCH or minimac? == |
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| </source> | | </source> |
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| + | == Further Time Savings == |
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| + | The recipe above imputes whole chromosomes, one a time. A further time savings is possible by imputing chromosomes in chunks, a process that can be facilitated using the [[ChunkChromosome]] tool. |
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| == X Chromosome Imputation == | | == X Chromosome Imputation == |