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RAREMETAL METHOD

47 bytes added, 23:47, 8 April 2014
VT META ANALYSIS
<math>T_{VT}=\max(T_{b\left(f_1\right)},T_{b\left(f_2\right)},\dots,T_{b\left(f_m\right)})</math>
where the burden test statistic under any allele frequency threshold can be constructed from single variant meta-analysis statistics using
<math>T_{b\left(f_j\right)}=\boldsymbol{\phi}_{f_j}^\mathbf{T}\sum_{i=1}^n{\mathbf{U_i}}\bigg/\sqrt{\boldsymbol{\phi}_{f_j}^\mathbf{T}\left(\sum_{i=1}^n{\mathbf{V_i}}\right)\boldsymbol{\phi}_{f_j}} </math>
where <math>j</math> represents any allele frequency in a group of rare variants., <math>\boldsymbol{\phi}_{f_j}</math> is a
===SKAT META ANALYSIS===
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