Difference between revisions of "Biostatistics 666: Analysis of Low Pass Sequence Data"
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Latest revision as of 23:32, 1 December 2010
Objective
Discussion of the challenges involved in sequencing thousands of individual genomes. Introduction to the analysis of low pass sequence data.
Lecture Notes
Recommended Reading
- The 1000 Genomes Project (2010) A map of human genome variation from population-scale sequencing. Nature 467:1061-73
- Li Y, Willer CJ, Ding J, Scheet P and Abecasis GR (2010) MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol 34:816-834
- Le SQ and Durbin R (2010) SNP detection and genotyping from low-coverage sequencing data on multiple diploid samples. Genome Research (in press)