Changes

   MINMAXFREQ ON

   MINMAXFREQ ON

METAL can optionally track the effect allele frequency across all files and report its mean, minimum and maximum.  These can be quite useful to check that allele frequencies are similar across different cohorts after METAL performs all strand alignment. Large differences in allele frequencies across studies can suggest inconsistent naming of alleles across studies. METAL requires all input files to have an allele frequency column when this feature is turned on. To specify the column header for allele frequency information, use the <code>FREQLABEL</code> command.

METAL can optionally track the effect allele frequency across all files and report the mean, minimum and maximum effect allele frequency.  These can be quite useful to check that allele frequencies are similar across different cohorts after METAL performs all strand alignment. Large differences in allele frequencies across studies can suggest inconsistent naming of reference alleles across studies. METAL requires all input files to have an allele frequency column when this feature is turned on. To specify the column header for allele frequency information, use the <code>FREQLABEL</code> command.

=== Custom Variables ===

=== Custom Variables ===