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RelativeFinder (view source)

Revision as of 04:17, 23 November 2010

202 bytes removed ,  04:17, 23 November 2010
→‎Current Limitations and Todo List
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== Download ==
 
== Download ==
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A source package is available for download from [http://www.sph.umich.edu/csg/abecasis/downloads/generic-relativeFinder-2010-08-12.tar.gz here].
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A source package is available for download from [http://www.sph.umich.edu/csg/abecasis/downloads/generic-relativeFinder-2010-08-13.tar.gz here].
    
== Current Limitations and Todo List ==
 
== Current Limitations and Todo List ==
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The current implementation does not include support for X linked markers and should only be used with autosomal markers.
 
The current implementation does not include support for X linked markers and should only be used with autosomal markers.
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The current implementation looks for a pair of files called ''testCases.dat'' and ''testCases.ped'' in the current working directory. This pair of files specifies alternate relationships to be considered.
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The current implementation simply reports the most likely relationship and the difference in log-likelihood between this relationship and the originally specified relationship. It would be better to use an E-M algorithm to calculate a prior probability for each relationship and to only report as problematic pairs where the posterior probability of a mis-specified relationship is high.
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The current implementation simply reports the most likely relationship and the difference in likelihood between this relationship and the originally specified relationship. It would be better to use an E-M algorithm to calculate a prior probability for each relationship and to only report as problematic pairs where the posterior probability of a mis-specified relationship is high.
 
Retrieved from "http://genome.sph.umich.edu/wiki/Special:MobileDiff/1922...2548"

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