From Genome Analysis Wiki
Jump to navigationJump to search
202 bytes removed
, 04:17, 23 November 2010
Line 93: |
Line 93: |
| The current implementation does not include support for X linked markers and should only be used with autosomal markers. | | The current implementation does not include support for X linked markers and should only be used with autosomal markers. |
| | | |
− | The current implementation looks for a pair of files called ''testCases.dat'' and ''testCases.ped'' in the current working directory. This pair of files specifies alternate relationships to be considered.
| + | The current implementation simply reports the most likely relationship and the difference in log-likelihood between this relationship and the originally specified relationship. It would be better to use an E-M algorithm to calculate a prior probability for each relationship and to only report as problematic pairs where the posterior probability of a mis-specified relationship is high. |
− | | |
− | The current implementation simply reports the most likely relationship and the difference in likelihood between this relationship and the originally specified relationship. It would be better to use an E-M algorithm to calculate a prior probability for each relationship and to only report as problematic pairs where the posterior probability of a mis-specified relationship is high. | |